Status:
UNKNOWN
Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular Premolars
Lead Sponsor:
Cairo University
Conditions:
Necrotic Pulp
Eligibility:
All Genders
20-40 years
Phase:
PHASE2
PHASE3
Brief Summary
The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using Moringa oleifera leaf extract solution during chemo-mechanical pre...
Eligibility Criteria
Inclusion
- Systematically healthy patient (ASA I,II).
- Age between 20 and 55 years
- Male or female.
- Asymptomatic mandibular premolar teeth diagnosed with pulp necrosis with apical periodontitis.
- Radiographic examination using Digora intraoral periapical sensor plate and software (Digora; Soredex, Helsinki, Finland) showing mandibular premolars with (smaller than 3 mm (0-2 mm)) periapical radiolucency.
Exclusion
- Medically compromised patients having significant systemic disorders. (ASA III or IV).
- History of intolerance to NSAIDS.
- Teeth with:
- Immature roots
- Vital pulp tissues.
- Association with swelling.
- Acute peri-apical abscess or acute exacerbation of a chronic abscess.
- Mobility Grade II or III.
- Previously accessed or endodontically treated
- Deep periodontal pockets more than 4 mm
- Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions.
- Patients who could not interpret the NRS.
- Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women were, also, excluded.
Key Trial Info
Start Date :
August 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2023
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05348824
Start Date
August 1 2022
End Date
April 1 2023
Last Update
August 9 2022
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