Status:
COMPLETED
IL-6 Regulation of Energy Stores During Recovery From an Acute Exercise Bout
Lead Sponsor:
Helga Ellingsgaard
Conditions:
Glycogen Depletion
Eligibility:
MALE
18-40 years
Phase:
NA
Brief Summary
The aim of the study is to investigate the role of exercise-induced IL-6 in regulating energy stores and energy metabolism during recovery after an acute exercise bout. To achieve this, 30 men will be...
Eligibility Criteria
Inclusion
- Physically active (defined as meeting the ACSM's guidelines of 2.5h per week of moderate to vigorous physical activity per week), young, healthy males will be included. Participants may be included in the study if they meet all the following criteria:
- Age ≥ 18 years and ≤ 40 years
- BMI \< 18 and \> 25 kg/m2
- Healthy (based on screening)
- Stable body weight for 6 months
- ≥ 2.5h/week moderate to vigorous physical activity
Exclusion
- • Cardiovascular disease
- Rheumatologic disease
- Metabolic disease
- Elite sports or high aerobic training status (VO2max \> 60 mL O2/min/kg)
- Frequent/chronic use of medications affecting physical performance or inflammation (NSAIDS, DMARDS, corticosteroids)
- Aspirin use \>100 mg/d
- Thyroid disease
- Current infection
- Aspartate amino transferase (AST) or alanine amino transferase (ALT) \>2x upper normal range
- History of carcinoma
- History of tuberculosis
- Ketogenic diet
- Smoking
- Anemia (hematocrit \<33%)
- Neutrophil count \<0,5x 109/l
- Thrombocytes \<50x 109/l or bleeding disorders
Key Trial Info
Start Date :
April 20 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 11 2022
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05349149
Start Date
April 20 2022
End Date
October 11 2022
Last Update
October 26 2022
Active Locations (1)
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1
Centre for Physical Activity Research, Rigshospitalet Section 7641
Copenhagen, Capital Region, Denmark, 2100