Status:
RECRUITING
Acute Normovolemic Hemodilution on Urine Neutrophil Gelatinase-associated Lipocalin Levels
Lead Sponsor:
University of Maryland, Baltimore
Conditions:
Acute Kidney Injury
Eligibility:
All Genders
18-70 years
Brief Summary
Acute normovolemic hemodilution (ANH) is performed as a blood conservation technique during surgical procedures with high risk for significant blood loss. It is done by taking out some of the patients...
Detailed Description
The study population will consist of 50 adult patients less than 70 years old undergoing elective coronary artery bypass graft (CABG) surgery with anticipated CPB duration less than 2 hours at the Uni...
Eligibility Criteria
Inclusion
- Elective Coronary Artery Bypass Graft Surgery
- Age 18-70 years
- Anticipated Cardiopulmonary Bypass Duration less than 2 hours
- Weight greater than 70kg
- Hemoglobin greater than 12 g/dL
Exclusion
- Emergency and redo cardiac surgery
- Renal insufficiency with serum creatinine greater than 1.25 mg/dL and/ or estimated GFR less than 60 mL/min/1.73 m2
- Heart Failure with EF \<40%
- Hepatic disease
- Pulmonary Disease, including pulmonary hypertension
- Inherited or Acquired Bleeding Disease
Key Trial Info
Start Date :
January 31 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05349292
Start Date
January 31 2024
End Date
June 1 2027
Last Update
March 21 2025
Active Locations (1)
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1
University of Maryland Medical Center
Baltimore, Maryland, United States, 21201