Status:
COMPLETED
Preclinical Imaging Biomarkers of Alzheimer's Disease Neuropathology in Young Adults With Youth-onset Diabetes: a Proof-of-concept Study
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
American College of Radiology
Conditions:
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Eligibility:
All Genders
18-40 years
Brief Summary
The goal of the study is to characterize preclinical Alzheimer's Disease and related dementias (AD/ADRD) neuropathology in a selected group of young adults with youth-onset diabetes, and an age-simila...
Detailed Description
The goal of the current proof-of-concept study is to characterize brain structural, functional, and molecular imaging biomarkers of preclinical Alzheimer's Disease and related dementias (AD/ADRD) neur...
Eligibility Criteria
Inclusion
- Part of the SEARCH for Diabetes in Youth study cohort or
- Age 18-40
- Without diabetes
Exclusion
- Head trauma with loss of consciousness \>30 minutes
- Claustrophobia
- Metal in the body
- Major psychiatric disorder (eg. schizophrenia, bipolar, and major depression)
- Neurological conditions affecting cognition (eg. epilepsy)
- Stroke
- If female, breastfeeding, plan to become pregnant or are pregnant
Key Trial Info
Start Date :
July 19 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 31 2023
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT05350514
Start Date
July 19 2022
End Date
May 31 2023
Last Update
November 30 2023
Active Locations (1)
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1
Lifecourse Epidemiology of Adiposity and Diabetes Center
Aurora, Colorado, United States, 80045