Status:

TERMINATED

Yogurt Supplementation to Alter Bone Biomarkers, the Gut Microbiota and Inflammation in Older Adults

Lead Sponsor:

University of Massachusetts, Lowell

Collaborating Sponsors:

University of Massachusetts, Worcester

The Lawrence Senior Center

Conditions:

Osteoporosis

Inflammation

Eligibility:

All Genders

50+ years

Phase:

NA

Brief Summary

Caribbean Latino adults are a vulnerable population at risk for developing osteoporosis. In addition to lifestyle factors, such as dietary intake, the investigators hypothesize that a unhealthy gut mi...

Detailed Description

Recruitment: A total of 40 Caribbean Latino men and women ≥50 y will be recruited and enrolled from Greater Lawrence, MA, USA. Subjects will be recruited using flyers distributed throughout the commu...

Eligibility Criteria

Inclusion

  • self-reported Caribbean Latino descent
  • at least 50 years of age

Exclusion

  • usual yogurt intake (\> 2 servings per week)
  • use of antibiotics in the past 6 months
  • regular weekly laxative use
  • self-reported osteoporosis
  • history of osteoporosis-related fracture
  • self-reported diagnosis of cancer
  • self-reported diagnosis of gastrointestinal diseases (Crohn's disease, ulcerative colitis, Clostridium difficile infection)
  • history of gastrointestinal alteration procedures (appendectomy, gastric bypass surgery)
  • use of osteoporosis drugs
  • use of steroids
  • use of chemotherapeutic agents

Key Trial Info

Start Date :

March 28 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 25 2020

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT05350579

Start Date

March 28 2019

End Date

March 25 2020

Last Update

April 28 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

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Lawrence Senior Center

Lawrence, Massachusetts, United States, 01840

Yogurt Supplementation to Alter Bone Biomarkers, the Gut Microbiota and Inflammation in Older Adults | DecenTrialz