Status:
COMPLETED
Exercise on Contactin-1 and Contactin-2 Level in Persons With Multiple Sclerosis
Lead Sponsor:
Firat University
Conditions:
Relapsing Remitting Multiple Sclerosis
Eligibility:
All Genders
18-65 years
Brief Summary
Little is known about the potential effects of exercise on the underlying disease mechanisms in multiple sclerosis (MS). Although contactin-1 and contactin-2 are known as two proteins involved in axon...
Detailed Description
This randomized controlled trial with a blinded outcome assessment evaluated an 8-week (3 sessions per week) training intervention to determine the effect of exercise on contactin-1 and contactin-2 in...
Eligibility Criteria
Inclusion
- definite diagnosis of RRMS according to the McDonalds criteria,
- 18 years or older,
- EDSS levels of 1.0 - 5.5, EDSS "pyramidal functions" sub score ≥2,
- who have not had an attack in the last 3 months,
- who were patients who did not receive steroid treatment for the last 3 months.
Exclusion
- orthopedic, cardiopulmonary, or systemic problems that prevent participation in exercises,
- pregnancy,
- started immunomodulatory treatment in the last 6 months,
- participated in resistance training 3 months before inclusion in the study.
Key Trial Info
Start Date :
November 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 4 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05351411
Start Date
November 1 2021
End Date
March 4 2022
Last Update
April 28 2022
Active Locations (1)
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1
Fırat university
Elâzığ, Turkey (Türkiye), 23100