Status:
UNKNOWN
Effects of Propofol on Auditory Event-related Potentials and Brain Functional Connectivity in Patients With Supratentorial Glioma
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Propofol
Glioma
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The growth of gliomas often infiltrates important brain tissues and impairs subcortical fiber transmission, resulting in changes in global brain network connectivity. Most of the current anesthesia de...
Eligibility Criteria
Inclusion
- Age 18 - 60 years old;
- American Society of Anesthesiologists (ASA) physical status rating I-II;
- Supratentorial glioma (frontal, temporal, parietal, insular ；WHO grade I-III);
- Native Chinese speaker;
- Signed informed consent.
Exclusion
- Mallampati airway class≥III;
- BMI\>30kg/m2;
- Combined OSAS or Stop-BANG score≥3;
- Hearing impairment
- Combined epilepsy symptoms
- Recurrent or multiple intracranial tumors
- Concomitant other psychiatric or neurological disorders
- Pregnancy and lactation
Key Trial Info
Start Date :
May 18 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05352685
Start Date
May 18 2022
End Date
September 30 2024
Last Update
November 1 2023
Active Locations (1)
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1
Beijing Tiantan Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100070