Status:

UNKNOWN

Morphological Changes of Ciliary Body and Trabecular Meshwork

Lead Sponsor:

Yune Zhao

Conditions:

Glaucoma

Myopia

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Glaucoma is the leading cause of irreversible blindness worldwide. Although the pathogenesis remains unclear, pathologic increase in intraocular pressure (IOP) due to blocked aqueous outflow through t...

Detailed Description

Glaucoma is the leading cause of irreversible blindness worldwide. Although the pathogenesis remains unclear, pathologic increase in intraocular pressure (IOP) due to blocked aqueous outflow through t...

Eligibility Criteria

Inclusion

  • Emmetropia/low myopia,high myopia, primary open-angle glaucoma without high myopia, and high myopia with primary open-angle glaucoma
  • have a good gaze to complete the test required inspection;

Exclusion

  • hypersensitivity to pilocarpine
  • History of eye surgery, including cataract surgery, anti-glaucoma surgery, corneal surgery, retinal surgery, and eye trauma
  • history of systemic diseases that may affect the eyes (such as diabetes, hypertension, etc.)
  • intraocular chronic inflammatory diseases (uveitis, etc.), retinal diseases (retinal detachment, diabetic retinopathy, retinitis pigmentosa, etc.)
  • Corneal scars and severe cataracts affect OCT imaging
  • Eye diseases (angle-closure glaucoma, abnormal anterior segment development, neovascularization, etc.) that can affect trabecular meshwork and Schlemm canal structure.

Key Trial Info

Start Date :

May 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2022

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT05352854

Start Date

May 1 2022

End Date

August 1 2022

Last Update

April 29 2022

Active Locations (0)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 0 (0 locations)

No Results Found

We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.