Status:
RECRUITING
Impact of Microbiome-changing Interventions on Food Decision-making
Lead Sponsor:
Max Planck Institute for Human Cognitive and Brain Sciences
Collaborating Sponsors:
Universitätsklinikum Leipzig
DFG - Deutsche Forschungs Gemeinschaft (German Research Foundation)
Conditions:
Overweight and Obesity
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The investigators aim to test the hypothesis that a microbiome-changing dietary intervention improves food decision-making and to determine the underlying microbiotal and metabolic mechanisms. To this...
Eligibility Criteria
Inclusion
- BMI \>= 25 kg/m2 or WHR \>= 0.9/0.85 (m/d, f)
- no MRI contra-indication
- written informed consent
Exclusion
- athletes
- occurrence of a clinically relevant psychiatric disease in the last 12 months, e.g. depression, substance abuse, eating disorders, schizophrenia
- any chronic inflammatory or malignant disease
- type 1 diabetes
- previous bariatric/gastric surgery
- pregnancy or breastfeeding woman
Key Trial Info
Start Date :
March 8 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05353504
Start Date
March 8 2022
End Date
December 1 2026
Last Update
April 29 2022
Active Locations (1)
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1
Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences
Leipzig, Germany