Status:
RECRUITING
Cognitive-motor Telerehabilitation in MS
Lead Sponsor:
Universitair Ziekenhuis Brussel
Collaborating Sponsors:
National MS Center Melsbroek
Research Foundation - Flanders (Fonds Wetenschappelijk Onderzoek)
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The primary goal of this project is providing evidence that a home-based combined cognitive-motor training program improves cognition in persons with multiple sclerosis (MS), compared to single cognit...
Eligibility Criteria
Inclusion
- Clinically definite multiple sclerosis (revised McDonald criteria 2017)
- Expanded Disability Status Scale (EDSS) below 6.0
- Digit span backwards z-score between \[-3 and -0.5\] standard deviations below the median of the normative values
- Age between 18 and 65
- Able to safely perform motor rehabilitation in the home situation (assessed by rehabilitation physician and/or occupational or physiotherapist)
Exclusion
- Cognitive rehabilitation within six months before inclusion
- Inpatient multidisciplinary rehabilitation program within three months before inclusion or planned inpatient program during trial
- Start of or switch in immunomodulator treatment within three months before inclusion
- Less than one month post-exacerbation
- Major psychiatric or medical disorder that could influence cognitive functions
- Combined vision with optimal correction below 0.6 on Snellen Visual Acuity Test
- Unable or unwilling to undergo EEG or MRI
- Refusing informed consent
Key Trial Info
Start Date :
September 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2027
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05355389
Start Date
September 1 2022
End Date
May 31 2027
Last Update
April 2 2025
Active Locations (2)
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1
Universitair Ziekenhuis Brussel
Brussels, Belgium
2
National MS Center Melsbroek
Melsbroek, Belgium