Status:

UNKNOWN

Bipolar Sealer for Reduction of Blood Loss in Anterior Total Hip Arthroplasties

Lead Sponsor:

North Texas Medical Research Institute, PLLC

Collaborating Sponsors:

Smith & Nephew, Inc.

Conditions:

Osteoarthritis, Hip

Blood Loss

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

The overall objectives and purpose of this study is to show that the Smith and Nephew Werewolf Fastseal 6.0 Bipolar Sealer is an effective tool to aide the surgical team in providing significant hemos...

Eligibility Criteria

Inclusion

  • The patient is to undergo a standard of care primary total hip replacement for degenerative joint disease. All devices are to be used according to the approved indications, this includes the FDA approved Werewolf Fastseal Bipolar Device.
  • The patient is expected to have an outpatient status and will be discharged \<23 hours.
  • Individuals who are able to speak, read, and comprehend the Institutional Review Board approved Informed Consent Document and willing and able to provide informed patient consent for participation in the study.
  • Individuals who are willing and able to complete follow-up visits and questionnaires as specified by the study protocol.
  • Individuals who are not bedridden per the discretion of the investigator (The intent of "not bedridden" means a permanent situation, not a temporary situation as in a hip fracture or trauma case).
  • Individuals who are a minimum age of 21 years and less than 80 years at the time of consent.

Exclusion

  • Active local or systemic infection.
  • Hematologic disease either inherited or acquired, that would predispose the patient to anemia or increased intra-operative blood loss
  • Currently taking anti-coagulation medications more than 81 mg aspirin every day.
  • Platelet disorder either inherited or acquired with a serum platelet level \<150,000 platelets per microliter.
  • Coagulopathy as seen with routine lab work
  • Unstable/uncontrolled cardiovascular disease such as congestive heart failure, hypertension, or renal disease such as GFR \<70, in the opinion of the investigative team and PI.
  • Excessive alcohol intake or tobacco use, in the opinion of the investigator.
  • Uncontrolled diabetes mellitus with hemoglobin a1c \>7.5%.
  • Established history of previous venous thrombotic events (VTE).
  • Loss of musculature, neuromuscular compromise or vascular deficiency in the affected limb rendering the procedure unjustified.
  • The subject is a woman who is pregnant or lactating.
  • Subject had a contralateral amputation.
  • Previous partial hip replacement in affected hip.
  • Subject has participated in a clinical investigation with an investigational product (drug or device) in the last three months.
  • Contralateral hip was replaced less than 3 months prior to surgery date, contralateral hip is already enrolled in the study, or simultaneous or staged hip replacement is planned
  • Subject is currently involved in any personal injury litigation, medical-legal or worker's compensation claims.
  • Subject was diagnosed and is taking prescription medications to treat a muscular disorder that limits mobility due to severe stiffness and pain such as fibromyalgia or polymyalgia.
  • Subject, in the opinion of the Investigator, is a drug or alcohol abuser or has a physical or psychological disorder that could affect their ability to complete patient reported questionnaires or be compliant with follow-up requirements.

Key Trial Info

Start Date :

April 29 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2024

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT05356637

Start Date

April 29 2022

End Date

February 1 2024

Last Update

October 31 2023

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Texas Health Sugery Center - Rockwall

Rockwall, Texas, United States, 75032

2

Baylor Scott & White - Lake Pointe Medical Center

Rowlett, Texas, United States, 75088