Status:

ACTIVE_NOT_RECRUITING

Anorexia Nervosa and Its Effects on Brain Function, Body Metabolism and Their Interaction in Adolescents

Lead Sponsor:

Turku University Hospital

Collaborating Sponsors:

University of Turku

Conditions:

Anorexia Nervosa

Eligibility:

FEMALE

13-17 years

Brief Summary

The aim of the research project is to investigate the neurological, physiological and behavioral underpinnings associated with the development of anorexia nervosa in adolescents. The goal of the proje...

Detailed Description

The aim of the project is to enable new ways to both predict and influence the course of anorexia nervosa. This is a three-year follow-up study in which we investigate the neurological and physiologic...

Eligibility Criteria

Inclusion

  • Inclusion criteria for anorexia nervosa patients:
  • Female sex
  • Age 13-17 years
  • Body mass index \< 17.5 kg/m2
  • Currently fulfilling modified Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) diagnosis criteria for anorexia nervosa with or without amenorrhea
  • Anorexia nervosa diagnosed within 2 yers
  • Inclusion criteria for healthy controls:
  • Female sex
  • Age 13-17 years
  • Body mass index 18,5-25 kg/m2
  • No lifetime history of obesity (Body mass index ≥ 30) or eating disorders
  • Exclusion criteria:
  • Any chronic illness or medication that could affect glucose metabolism or neurotransmission
  • Any other current mental disorder (excluding anorexia nervosa for the patient participants)
  • Severe previous mental disorder (excluding anorexia nervosa for the patient participants)
  • Smoking of tobacco, snuffing, or use of narcotics
  • Abusive use of alcohol

Exclusion

    Key Trial Info

    Start Date :

    January 1 2022

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    December 31 2027

    Estimated Enrollment :

    33 Patients enrolled

    Trial Details

    Trial ID

    NCT05357053

    Start Date

    January 1 2022

    End Date

    December 31 2027

    Last Update

    September 22 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

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    Turku PET Centre

    Turku, Finland, 20521