Status:

NOT_YET_RECRUITING

Effects of AlignBabyCleft (ABaCleft)

Lead Sponsor:

Universidad Complutense de Madrid

Conditions:

Cleft Lip

Cleft Palate

Eligibility:

All Genders

7-1 years

Phase:

NA

Brief Summary

Since the appearance of presurgical infant orthopedic (PSIO) as a treatment for patients with cleft lip and palate ( CLP) , numerous techniques have been described with the aim of aligning the displac...

Detailed Description

The AlingBabyCleft (AbaCleft) trial will be designed as a randomized controlled clinical trial, with an investigator blinded, superiority trial with two parallel arms. Active treatment will be planne...

Eligibility Criteria

Inclusion

  • Patients selected for the clinical trial must meet these criteria after randomization:
  • All patients born at term, without any syndrome associated with CLP, aged between 7 days and one month of life, referred from the different hospitals of the Spanish Health System, will be included in the study.
  • No distinction will be made on the basis of race or ethnic group to which the participants belong.
  • Any patient will be discriminated due to distance from their place of residence.
  • Participants must agree to attend regular check-ups.
  • All patients who agree to be part of the experimental study must previously sign the specific informed consent designed for this purpose.

Exclusion

  • Caregivers who are not fluent in the Spanish language will be excluded in order to understand and assimilate all the instructions provided for treatment compliance.
  • Patients who do not comply with the regimen of visits to the orthodontic department, and for whom a correct control of the evolution of the treatment cannot be guaranteed, will be excluded from the study.
  • Lack of collaboration or non-compliance with the use of the clear aligners will also be considered grounds for exclusion.
  • Patients with soft tissue bands should also be excluded from our study.

Key Trial Info

Start Date :

November 21 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2028

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05357092

Start Date

November 21 2025

End Date

November 1 2028

Last Update

April 25 2025

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