Status:
RECRUITING
A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation
Lead Sponsor:
Mayo Clinic
Conditions:
Atrial Fibrillation
Eligibility:
All Genders
60+ years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to test if a nerve block procedure called a stellate ganglion block can help decrease the chance of atrial fibrillation after surgery. Atrial fibrillation is the abnormal,...
Detailed Description
The investigator hypothesizes that stellate ganglion blockade with local anesthetic performed prior to cardiac surgery will reduce the incidence and duration of postoperative atrial fibrillation (POAF...
Eligibility Criteria
Inclusion
- Patient presenting for cardiac surgery at the Mayo Clinic in Rochester, Minnesota.
- Patients scheduled to undergo mitral or aortic valve surgery with or without coronary artery bypass grafting.
Exclusion
- Patients with a history of permanent atrial fibrillation, left or right ventricular assist device implantation or explantation.
- Patients with procedures not requiring cardiopulmonary bypass.
- Patients with procedures requiring deep hypothermic circulatory arrest.
- Patients with active infection or sepsis.
- Pre-operative immunosuppressive medication use (including steroid use).
- Pre-operative anti-arrhythmic medication use (aside from beta-blockers).
- Patients with Immunodeficiency syndrome.
- Patients with known neurologic disorder.
- Patients requiring left internal jugular central line placement.
- Performance of Maze procedures or left atrial appendage ligation procedures will not exclude patients from potential enrollment as atrial fibrillation still occurs postoperatively while the scarring from the Maze procedure forms.
Key Trial Info
Start Date :
April 19 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT05357690
Start Date
April 19 2023
End Date
December 1 2026
Last Update
May 14 2025
Active Locations (1)
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1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905