Status:
COMPLETED
Vitamin D for Cognition in Bipolar Disorder
Lead Sponsor:
Taipei City Hospital
Conditions:
Bipolar Disorder
Eligibility:
All Genders
20-65 years
Phase:
NA
Brief Summary
Conduct randomized double-blind controlled trial (RCT), to examine the effects of vitamin D on cognitive performance in euthymic BD.
Detailed Description
Bipolar disorder (BD) is a chronic mental disease related to recurrent episodes along with cognitive or functional decline. Comparing efficacy of pharmacological interventions targeting to treat cogni...
Eligibility Criteria
Inclusion
- Patients who diagnosed with BD-I based on the Diagnostic and Statistical Manual (DSM-IV) criteria are consecutively referred by board-certified psychiatrists in Taipei City Hospital, Songde branch.
- Age of participants should range from 20 to 65 years old.
- No history of vitamin D supplementation within three months before the study.
- The BD patients in their euthymic state (both Hamilton Depression Rating Scale and Young Mania Rating Scale ≤ 8) and no change of their psychoactive medications in recent three months.
Exclusion
- With known substance use disorder (except nicotine use disorder)
- With any disorder with known neurological symptoms or complications (ex. brain injury, stroke or brain lesions)
- Comorbid with schizophrenia spectrum disorders
- With active physical condition (such as renal impairment, hepatic failure…) or pregnancy
- Inability to complete the standard assessment or incapability of providing informed consent
Key Trial Info
Start Date :
May 3 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 20 2023
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT05357859
Start Date
May 3 2022
End Date
November 20 2023
Last Update
November 22 2023
Active Locations (1)
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1
Taipei City hospital
Taipei, Taiwan