Status:

COMPLETED

Investigating Neuronal and Peripheral Markers of Brain Heart Interaction in Healthy Participants Under Stress

Lead Sponsor:

University of Heidelberg Medical Center

Collaborating Sponsors:

University of Cologne

Conditions:

Heart Rate

Magnetic Resonance Imaging

Eligibility:

All Genders

18-55 years

Brief Summary

This study seeks to investigate which regions of the brain are relevant in the regulation of cardiac control and how the interplay between HRV and those regions change during different physiological s...

Detailed Description

Heart rate variability (HRV) is an important indicator of an organism's ability to adapt and regulate autonomic cardiac function. High heart rate variability is an indicator of good adaptability to ph...

Eligibility Criteria

Inclusion

  • Over age of 18 years.
  • Right-handedness.
  • Normal or corrected-to-normal vision.

Exclusion

  • History of head injury or surgery
  • History of neurological disorder
  • Severe psychiatric comorbidity (psychosis, bipolar disorder, substance abuse)
  • Smoking
  • Borderline personality disorder
  • Current psychotropic medication
  • Inability to undergo fMRI scan (e.g. metallic implants, claustrophobia, pacemakers)
  • Pregnancy

Key Trial Info

Start Date :

February 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2023

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT05358314

Start Date

February 1 2022

End Date

September 1 2023

Last Update

November 29 2023

Active Locations (1)

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1

University Hospital Heidelberg

Heidelberg, Germany

Investigating Neuronal and Peripheral Markers of Brain Heart Interaction in Healthy Participants Under Stress | DecenTrialz