Status:

COMPLETED

Family Diabetes Prevention Program Pilot Study

Lead Sponsor:

Johns Hopkins University

Collaborating Sponsors:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

PreDiabetes

Overweight and Obesity

Eligibility:

All Genders

5+ years

Phase:

NA

Brief Summary

This study will examine the feasibility and acceptability of a family-oriented augmentation of the Diabetes Prevention Program lifestyle intervention (DPP), called the Family DPP. It will also prelimi...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for the Intervention Arm:
  • For ADULT participants, inclusion criteria are:
  • Meeting eligibility criteria for the CDC's National Diabetes Prevention Program lifestyle intervention, which are:
  • 18 years of age and older;
  • not pregnant at time of enrollment;
  • body mass index (BMI) of ≥25 kg/m2 (≥23 kg/m2 , if of Asian race);
  • meet one of the following: a) have prediabetes (defined as fasting glucose of 100-125 mg/dL; plasma glucose measured 2 hours after 75 gm glucose load of 140 to 199 mg/dL, or A1c of 5.7% to 6.4%); b) history of clinically diagnosed gestational diabetes mellitus (GDM) during a previous pregnancy; c) high risk for diabetes based on CDC or American Diabetes Association (ADA) Diabetes Screening Test).
  • AND
  • being a primary caregiver of at least one eligible child aged 5 through 12 years at time of recruitment (defined as caring for the child, with a responsibility for the child's food, sleep and activity habits, at least 3 days out of the week)
  • For CHILD participants, inclusion criteria are:
  • being aged 5 through 12 years at time of recruitment;
  • not having a medical condition which leads to inability to comply with general pediatric dietary or physical activity goals; AND
  • not concurrently enrolled in a structured weight management program.
  • Exclusion Criteria for Intervention Arm:
  • For ADULT participants, exclusion criteria include
  • Conditions that would exclude their participation in the DPP lifestyle intervention which include:
  • pregnancy;
  • having end-stage renal disease;
  • having type 1 or type 2 diabetes.
  • They will also be excluded if they are concurrently enrolled in a structured weight management program.
  • For CHILD participants: exclusion criteria include:
  • having a medical condition which leads to inability to comply with general pediatric dietary or physical activity goals;
  • being enrolled in a structured weight management program.
  • For the Control Arm/Concurrent Control Group, this will only enroll ADULT participants.
  • The inclusion criteria are:
  • Being a participant in the Brancati Center's Diabetes Prevention Program, in a group that has started within 6 months of Intervention Arm group start
  • Lives with a child less than 18 years of age in their household

Exclusion

    Key Trial Info

    Start Date :

    July 8 2022

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    February 19 2024

    Estimated Enrollment :

    34 Patients enrolled

    Trial Details

    Trial ID

    NCT05358444

    Start Date

    July 8 2022

    End Date

    February 19 2024

    Last Update

    July 8 2025

    Active Locations (1)

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    Johns Hopkins University School of Medicine

    Baltimore, Maryland, United States, 21205