Status:
COMPLETED
Pharmacokinetic Analysis of Bupivacaine in the Presence and Absence of Perineural Dexamethasone in Axillary Blockade
Lead Sponsor:
University of Chile
Conditions:
Analgesia
Acute Pain
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The investigators will conduct a prospective, randomized, double-blinded study using an axillary brachial plexus block in patients undergoing elective surgery of the distal forearm and hand to charact...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists classification 1-2
- Real weight between 80 and 100 kg
- Body mass index between 20 and 30
Exclusion
- Adults who are not capable of giving their own consent
- Medical history or physical findings of pre-existing neuropathy
- Coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. platelets ≤ 100, International Normalized Ratio ≥ 1.4 or prothrombin time ≥ 50)
- Renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. creatinine ≥ 100)
- Hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. transaminases ≥ 100)
- Allergy to local anesthetics (LAs)
- Pregnancy
- Previous surgery in the axillary region of the surgical side
Key Trial Info
Start Date :
June 28 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 24 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05359731
Start Date
June 28 2022
End Date
April 24 2023
Last Update
October 17 2023
Active Locations (1)
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1
Hospital Clínico Universidad de Chile
Santiago, Metropolitan, Chile