Status:

COMPLETED

Effects of Degludec/Liraglutide on Time in Range, Inflammation and Endothelial Function vs Insulin Basal Bolus in Diabetic Inpatients

Lead Sponsor:

University of Palermo

Conditions:

Diabetes Mellitus, Type 2

Eligibility:

All Genders

18-90 years

Phase:

PHASE4

Brief Summary

The study aims to evaluate the effects of Insulin Degludec/Liraglutide on glycemic variability assessed by continuous glycemic monitoring with the function time in range, serum markers of inflammation...

Detailed Description

100 patients with type 2 diabetes mellitus were recruited at the Internal Medicine with Stroke care ward of the University hospital of Palermo "P. Giaccone" from April 2022 to April 2024. 50 patients ...

Eligibility Criteria

Inclusion

  • Diabetes mellitus type 2
  • Mild-moderate Hyperglycemia (180-400 mg/dl)
  • Acute events (Pneumonia, Acute cardiac Ischemia, Ictus, IVU)

Exclusion

  • Diabetes mellitus type 1
  • Diabetic ketoacidosis
  • Hyperosmolar coma
  • Severe hypoglycaemia
  • Acute Pancreatitis
  • Cancer
  • use of corticosteroids
  • pregnancy
  • Chronic kidney disease (\< 30 ml/min) or hemodialysis

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 20 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05360537

Start Date

April 1 2021

End Date

April 20 2022

Last Update

December 15 2023

Active Locations (1)

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1

Internal Medicine Ward, University of Palermo

Palermo, Italy, 90127