Status:

COMPLETED

Sensorimotor Training Using Whole Body Vibration Exercise to Reduce Chemotherapy-induced Peripheral Neuropathy

Lead Sponsor:

Karolinska Institutet

Conditions:

Breast Neoplasm, Exercise

Eligibility:

FEMALE

18-80 years

Phase:

NA

Brief Summary

CIPN is induced by neurotoxic chemotherapeutic agents and manifests with sensory and/or motor deficits. It is associated with significant disability and poor recovery. Common symptoms include pain, al...

Detailed Description

Aim: To (a) compare the effects of WBV exercise compared to regular cardiovascular and resistance exercise (CAR) on the primary outcome of (a) CIPN symptoms and secondary outcomes of (b) balance, phys...

Eligibility Criteria

Inclusion

  • patients with breast cancer, aged 18-80 years,
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0-2,
  • completed chemotherapy in the past 3 months. Experiencing symptoms of CIPN

Exclusion

  • pre-existing neuropathy of other cause (eg, diabetes),
  • given contraindications for WBV including instable bone metastases and severe cardiovascular disease.

Key Trial Info

Start Date :

October 17 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 30 2024

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT05361018

Start Date

October 17 2022

End Date

October 30 2024

Last Update

November 18 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Karolinska University Hospital

Stockholm, Sweden, 11447