Status:

UNKNOWN

Transarterial Chemoembolization With Lipiodol in the Treatment of Initial Unresectable Gastric Cancer (GC)

Lead Sponsor:

Gang Wu

Conditions:

Gastric Cancer

Embolization

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

This is a prospective, open-labelled study to evaluate the efficacy and safety of sequential transarterial chemoembolization with lipiodol and neoadjuvant chemotherapy in the treatment of Initial unre...

Eligibility Criteria

Inclusion

  • Pathological and imaging diagnosis of gastric adenocarcinoma with initial unresectable R0;
  • Age (18-80 years old) and gender are not limited;
  • No extragastric organ transfer;
  • No serious diseases of the heart, liver, lung, kidney and other organs;
  • Expected survival time \> 3 months;
  • Physical performance status score ECOG ≤1 point;
  • Females of reproductive age must have a negative pregnancy test; or male and female patients must agree to use effective contraception during treatment and within 1 year thereafter.

Exclusion

  • Poor coagulation function, INR\>1.5, or ongoing anticoagulation therapy or known bleeding diseases;
  • WBC \<3000/mm3 or platelet count \<50000/mm3;
  • AST and/or ALT \> 3 times the upper limit of normal;
  • Comorbidities or social environment that can cause subjects to fail to follow the research plan or even endanger patient safety;
  • The patient has other primary tumors.

Key Trial Info

Start Date :

June 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05361161

Start Date

June 1 2022

End Date

December 1 2025

Last Update

May 24 2022

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