Status:

COMPLETED

Delayed Antibiotic Therapy in General Practice

Lead Sponsor:

CNGE Conseil

Conditions:

AOM - Acute Otitis Media

Eligibility:

All Genders

6+ years

Brief Summary

Introduction In 2019, France was the 4th highest consumer of antibiotics in Europe. Among the interventions proposed to reduce antibiotic prescribing, delayed prescribing deserves particular attention...

Detailed Description

In 2018, France was the third country in Europe for antibiotic consumption. Each year, 33,000 deaths in Europe, from which 12,500 in France, could be due to antibiotic-resistant bacteria . Without cha...

Eligibility Criteria

Inclusion

  • Age greater than 6 months
  • At least one of the following signs:
  • moderate to severe tympanic membrane bulge or recent onset of otorrhea not caused by otitis externa,
  • mild tympanic membrane bulge associated with either:
  • recent onset (less than 48 hours) of otalgia (or holding, pulling, rubbing the ear in a child who does not speak) or,
  • tympanic erythema
  • Enrolled in a social security plan or beneficiary of such a plan.
  • Patient who has given oral non-objection after being fully informed about the protocol.

Exclusion

  • \- AOM in the previous 3 months or recurrent AOM (≥ 3 in 6 months or ≥ 4 in 12 months)
  • Presence of paracentesis tubes or perforated tympanic membrane
  • Acute complication of otitis (mastoiditis, meningitis, intracranial abscess, sinusal thrombosis or facial nerve paralysis)
  • Additional intercurrent bacterial infection such as diagnosed or suspected pneumonia
  • Symptomatology that suggests a more serious condition to the clinician
  • Hospitalization or emergency care required
  • Patients at risks of complication (immunosuppression)
  • Associated severe acute pathology
  • Cranio-facial malformation, down syndrom, cystic fibrosis
  • Antibiotic therapy in the previous seven days
  • Minor patient not accompanied by a legal representative (father or mother)
  • Patients already included in the study
  • Patients who does not speak french
  • Person subject to a legal protection measure
  • Persons deprived of liberty
  • Pregnant women, parturients and breastfeeding mothers

Key Trial Info

Start Date :

October 20 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 2 2024

Estimated Enrollment :

865 Patients enrolled

Trial Details

Trial ID

NCT05361239

Start Date

October 20 2022

End Date

May 2 2024

Last Update

July 3 2024

Active Locations (1)

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1

MSPU Jacques Prévert10 place George Sand

Montigny-le-Bretonneux, France, 78180