Status:

COMPLETED

ProduceRx: Improving Weight and Cardiovascular Risk in Adults With Food Insecurity and Obesity

Lead Sponsor:

University of Pennsylvania

Conditions:

Obesity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a pilot randomized controlled trial to assess the effects of providing produce vouchers during behavioral weight loss treatment in 40 adults with obesity and food insecurity. Participants will...

Detailed Description

The proposed investigation is a single-site, pilot RCT to assess the effect of BWL and produce vouchers (ProduceRx) on diet quality, weight loss and cardiovascular risk factors among adult participant...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years old
  • BMI ≥ 30 kg/m2
  • Food insecurity as assessed by the two-item "hunger vital sign"
  • Subjects must:
  • have reliable telephone or Internet service to communicate with study staff
  • plan to remain in the Philadelphia area for the next 6 months or more
  • Understand and be willing to comply with all study-related procedures and agree to participate in the study by giving written informed consent.

Exclusion

  • Pregnant, nursing, or plans to become pregnant in the next 6 months
  • Serious medical risk such as uncontrolled diabetes, cancer, congestive heart failure, or recent cardiac event (e.g., myocardial infarction or stroke within the past 6 months)
  • Clinically significant hepatic or renal disease
  • History of (or plans for) bariatric surgery
  • Current psychiatric disorder that significantly interferes with daily living
  • Self-reported alcohol or substance abuse within the past 12 months
  • Use in past 3 months of medications known to induce significant weight loss (i.e., prescription weight loss medications) or weight gain (e.g., chronic use of oral steroids, second generation antipsychotics)
  • Loss of ≥ 10 lb of body weight within the past 3 months
  • Participation in a structured weight loss program in the prior 6 months
  • Inability to walk 2 blocks comfortably or engage in some other form of aerobic activity (e.g., swimming)
  • Participant from same household
  • Inability to attend treatment and/or assessment visits
  • Lack of capacity to provide informed consent
  • Any serious or unstable medical or psychological condition that, in the opinion of the investigator, would compromise the patient's safety or successful participation in the study

Key Trial Info

Start Date :

April 26 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 2 2023

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT05362747

Start Date

April 26 2022

End Date

June 2 2023

Last Update

July 12 2023

Active Locations (1)

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1

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104