Status:

RECRUITING

Selective CT for Anticoagulated Head Injured Patients

Lead Sponsor:

Dr. Kerstin de Wit

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Conditions:

Head Injury

Traumatic Brain Injury

Eligibility:

All Genders

16+ years

Brief Summary

The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are...

Detailed Description

This is a prospective cohort study enrolling 4000 anticoagulated patients presenting with blunt head trauma to the emergency department. Emergency physicians will record the presence or absence of cli...

Eligibility Criteria

Inclusion

  • Age ≥16 years
  • Presents to the emergency department after a head injury
  • Patient has a head CT in the emergency department
  • Is a current anticoagulant user

Exclusion

  • Head injury occurred \>48 h before patient's arrival to the emergency department
  • Penetrating head injury
  • Previously enrolled
  • Patient resides outside of the hospital's catchment area
  • Patient was transferred from another emergency department following neuroimaging
  • Patient was not managed by the emergency or trauma physician in the emergency department
  • Leaves the emergency department prior to completion of their medical assessment

Key Trial Info

Start Date :

March 17 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2027

Estimated Enrollment :

4000 Patients enrolled

Trial Details

Trial ID

NCT05364749

Start Date

March 17 2022

End Date

September 30 2027

Last Update

May 10 2024

Active Locations (7)

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Page 1 of 2 (7 locations)

1

University of British Columbia

Vancouver, British Columbia, Canada, V6T 1Z4

2

Hamilton Health Sciences Corporation

Hamilton, Ontario, Canada, L8L 2X2

3

Kingston Health Sciences Centre

Kingston, Ontario, Canada, N3T 6P9

4

Ottawa Hospital Research Institute

Ottawa, Ontario, Canada, K1H 8L6