Status:
COMPLETED
Clinical Study On Acute Radiotherapy-Induced Oral Mucositis In Patients With Locally Advanced Head And Neck Tumors
Lead Sponsor:
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Conditions:
Head and Neck Cancer
Eligibility:
All Genders
18-75 years
Phase:
PHASE3
Brief Summary
To explore a more efficient and scientific clinical treatment plan for acute radiotherapy-induced oral mucositis(RIOM/RTOM).it is hoped that the drug combination can more effectively improve the cure ...
Eligibility Criteria
Inclusion
- Head and neck cancer was confirmed by patholog
- Received radical radiotherapy, and were observed and treated by RTOM in the stomatology department
- Age range: 18-75 years old
- The estimated survival period is more than 6 months, and the card functional status score (KPS) is 70
- There are no diseases that affect the treatment of oral mucositis, such as mouth opening restriction, Sjogren's syndrome, etc.
- Sign the informed consent form
Exclusion
- Failed to complete radiotherapy, or delayed radiotherapy more than 2 weeks than planned
- There are previous oral mucosal diseases, such as oral lichen planus and pemphigus, which are not effectively controlled or still need long-term drug treatment
- There are other diseases that affect radiotherapy, such as severe organ function injury, chronic infectious diseases, etc.
- Had received radiotherapy for head and neck for other diseases;
- The expected survival time is less than 6 months;
- Refuse to provide personal information or sign informed consent
- The investigator judged other conditions that might affect the conduct of the clinical study and the determination of the study results.
Key Trial Info
Start Date :
August 17 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2023
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05364918
Start Date
August 17 2020
End Date
March 31 2023
Last Update
April 24 2023
Active Locations (1)
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1
Yu Zeng
Guangzhou, Guangdong, China, 510000