Status:
COMPLETED
Skeletal Muscle and Adipose Tissue Responses After Acute Exercise: Comparing Effects of Three Different Intensities
Lead Sponsor:
University of Michigan
Conditions:
Cellular Responses Within Skeletal Muscle in Response to Exercise of Different Intensities
Relationship Between the Cellular Responses in Skeletal Muscle and the Changes in the Metabolomic Profile
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The study will assess the exercise-induced changes in chromatin accessibility and gene expression in a cell type-specific manner in skeletal muscle from healthy adults in response to exercise at three...
Eligibility Criteria
Inclusion
- Age:18-40
- Body Mass Index: 20-30 kg/m2
- Must engage in regularly planned aerobic-type exercise at moderate-vigorous intensity, 3 times per week for at least 30-60 minutes/session
- Women must have regularly occurring menses and must be premenopausal
- Subject willingness to opt-in for the Michigan Genomics Initiative (MGI) Repository
Exclusion
- Evidence/history of cardiovascular or metabolic disease.
- Taking anti-coagulate medications or medications known to affect metabolism or inflammation
- Weight instability ≥ ±3kg in the last 6 months
- Tobacco or e-cigarette users
- Women must not be pregnant or actively lactating
Key Trial Info
Start Date :
December 13 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 23 2023
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT05365334
Start Date
December 13 2021
End Date
June 23 2023
Last Update
July 26 2024
Active Locations (1)
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1
University of Michigan
Ann Arbor, Michigan, United States, 48109