Status:

COMPLETED

Early Interventional Treatment for Cancer Pain

Lead Sponsor:

Dana-Farber Cancer Institute

Collaborating Sponsors:

Medtronic

Conditions:

Cancer Pain

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

The purpose of the study is to evaluate how feasible and beneficial it is to refer patients with cancer pain to a doctor who specializes in pain management, including procedures to relieve pain, and w...

Detailed Description

This is a single arm pilot study evaluating a new system of referral and pain evaluation for patients with advanced solid tumors and moderate-to-severe pain who are not already on high-dose opioids to...

Eligibility Criteria

Inclusion

  • Diagnosis of a metastatic, or locally advanced unresectable malignancy
  • Anticipated prognosis of more than 6 months according to the primary oncologist
  • Age greater than 21 years
  • Persistent pain with an average pain rating of 4 or greater on an 11-point numeric rating scale (NRS) from 0-10 where 10 is considered the most severe.
  • Pain has persisted for at least 2 weeks
  • Pain is due to cancer or sequelae of cancer treatment

Exclusion

  • Primary pain syndrome is sensory peripheral neuropathy
  • Patient is taking more than 200 morphine milligram equivalents (MMEs) per day on average, at the time of recruitment.
  • Currently cared for by interventional pain management specialist
  • Receipt of prior pain intervention (e.g. celiac neurolysis)
  • Bleeding diathesis, uncontrollable infection, or other contra-indications to pain interventions
  • History of opioid misuse disorder
  • Inability to speak English
  • Cognitive impairment or any other disorder that would impede study participation and survey completion
  • If patients are unable to complete the baseline survey, they will no longer be considered eligible for the study; this will serve as an indication of barriers to participation that would make them unable to comply with study procedures.

Key Trial Info

Start Date :

June 2 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 26 2024

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05366413

Start Date

June 2 2022

End Date

October 26 2024

Last Update

April 16 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02215

2

Dana Farber Cancer Institute

Boston, Massachusetts, United States, 02215