Status:
COMPLETED
A Study to Learn About the Study Medicine (Called Avelumab) in People With Advanced Urothelial Cancer After Chemotherapy
Lead Sponsor:
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Conditions:
Urothelial Cancer
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Avelumab) in people with advanced urothelial (bladder) cancer (UC) whose disease hasn't worsen...
Detailed Description
The primary objective of this study is to estimate real-world overall survival (rwOS) in a real-world cohort of patients treated with avelumab monotherapy for the first-line maintenance treatment of a...
Eligibility Criteria
Inclusion
- Patients with a diagnosis of locally advanced or metastatic UC, either de novo or relapsed
- Patients received 1L platinum-based chemotherapy and had stable disease, partial response, or complete response to this treatment
- Patients received avelumab as indicated as a monotherapy for the first-line maintenance treatment of adult patients with locally advanced or metastatic UC who are progression-free following platinum-based chemotherapy
- Patients aged ≥18 years on the date that they commenced avelumab -
Exclusion
- Patients whose hospital records are not available for review
- Patients who are receiving an investigational medicinal product as part of a clinical trial at the time of maintenance therapy with avelumab
Key Trial Info
Start Date :
June 29 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 27 2024
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT05366725
Start Date
June 29 2022
End Date
June 27 2024
Last Update
December 2 2025
Active Locations (10)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospitals Bristol
Bristol, United Kingdom, BS1 3NU
2
Beatson West of Scotland Cancer Centre
Glasgow, United Kingdom, G12 0YN
3
Royal Surrey County Hospital
Guildford, United Kingdom, GU2 7XX
4
University College London Hospital
London, United Kingdom, NW1 2PG