Status:

COMPLETED

Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination on Postoperative Opioid Consumption

Lead Sponsor:

Seoul National University Hospital

Collaborating Sponsors:

Kyongbo Pharmaceutical

Conditions:

Postoperative Pain

Eligibility:

All Genders

19-80 years

Phase:

NA

Brief Summary

This prospective, randomized, double-blinded study is designed to evaluate the postoperative analgesic effect of the intravenous acetaminophen/ibuprofen fixed-dose combination in patients undergoing v...

Detailed Description

Adult patients undergoing elective unilateral VATS wedge resection, segmentectomy, or lobectomy are randomly allocated to receive intravenous acetaminophen (1000 mg)/ibuprofen (300 mg) fixed-dose comb...

Eligibility Criteria

Inclusion

  • Patients scheduled to undergo elective unilateral VATS segmentectomy or lobectomy under general anesthesia
  • American Society of Anesthesiologists (ASA)physical classification I-II
  • Consent to IV-patient controlled analgesia use
  • Willingness and ability to sign an informed consent document

Exclusion

  • Do not understand our study
  • Allergies to anesthetic or analgesic medications
  • Continuous local anesthetics infiltration for postoperative pain control
  • Patients who receive mechanical ventilation more than 2 hours after surgery
  • Pregnancy/Breastfeeder
  • Medical or psychological disease that can affect thetreatment response

Key Trial Info

Start Date :

October 3 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 15 2023

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT05366777

Start Date

October 3 2022

End Date

October 15 2023

Last Update

December 19 2023

Active Locations (1)

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1

Seoul National University Hospital

Seoul, South Korea, KS013