Status:
RECRUITING
Effect of Breastfeeding on Lipid Profile and Cardiovascular Risk Markers in Women with Familial Hypercholesterolemia
Lead Sponsor:
Oslo University Hospital
Collaborating Sponsors:
University of Oslo
Conditions:
Familial Hypercholesterolemia
Eligibility:
FEMALE
18+ years
Brief Summary
The study aims to investigate the effects of breastfeeding on lipid profile and cardiovascular risk markers in women with familial hypercholesterolemia (FH) compared to women without FH. Women with FH...
Detailed Description
Patients with familial hypercholesterolemia (FH) have elevated plasma levels of LDL-cholesterol from first years of life. Cholesterol burden through life defines risk of cardiovascular disease. In wom...
Eligibility Criteria
Inclusion
- Inclusion Criteria for women with FH:
- age 18 years or older,
- confirmed diagnosis of FH through genetic testing or clinical assessment based on the Dutch Lipid Clinic Network,
- singleton pregnancy in the third trimester,
- a sufficient command of Norwegian, Dutch, Czech or English language.
- Exclusion Criteria for women with FH:
- Not filling the inclusion criteria.
- Inclusion Criteria for women without FH:
- age 18 years or older,
- singleton pregnancy in the third trimester,
- a sufficient command of Norwegian or English language.
- Exclusion Criteria for women without FH:
- known pre-pregnancy hypercholesterolemia,
- a history of ASCVD.
Exclusion
Key Trial Info
Start Date :
May 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05367310
Start Date
May 1 2022
End Date
December 31 2026
Last Update
March 21 2025
Active Locations (3)
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1
Third Department of Internal Medicine, General University Hospital, First Faculty of Medicine, Charles University
Prague, Czechia
2
Department of Internal Medicine, Erasmus MC Cardiovascular Institute
Rotterdam, Netherlands
3
Oslo University Hospital
Oslo, Norway