Status:
RECRUITING
Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
Lead Sponsor:
Senthil Sadhasivam
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
PPAP
Spine Fusion
Eligibility:
All Genders
10-21 years
Phase:
NA
Brief Summary
The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse...
Detailed Description
Aim 1. Develop and implement a perioperative precision analgesia platform (PPAP) by linking genomics to opioid metabolism, CPIC guidelines, precision dosing, clinical safety, and personalizing analges...
Eligibility Criteria
Inclusion
- Children ages 10 to 21
- ASA physical status 1 to 3
- Undergoing Posterior-Lateral Spinal Fusion
- Receives in-patient opioids
- Prescribed opioids at discharge
Exclusion
- Serious illness
- Preoperative severe pain
- Preoperative opioid use or misuse
Key Trial Info
Start Date :
September 20 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT05367609
Start Date
September 20 2022
End Date
September 1 2026
Last Update
September 19 2025
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
University of California
San Francisco, California, United States, 38456
2
Riley Children's Hospital
Indianapolis, Indiana, United States, 46202
3
UPMC Children's Hospital
Pittsburgh, Pennsylvania, United States, 15224