Status:
COMPLETED
Dietary Protein Impact on Human Gut Health
Lead Sponsor:
Örebro University, Sweden
Conditions:
Healthy
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The overall aim of this project is to evaluate the quantity of dietary protein that affects gut protein metabolization and if the baseline measurements are stable.
Detailed Description
Healthy male and female adult subjects (n=39) will be recruited to take part in an evaluation study to determine the amount of dietary protein intake which influences gut-protein-derived metabolites p...
Eligibility Criteria
Inclusion
- Age 18-45 years
- Body mass index (BMI) 18,5-30 kg/m2
- Weight stable within the previous 3 months
- Maintenance of the usual physical activity habits during the study
- Intake of fibre between 15 and 25 g per day (evaluated by 3 food diaries or 24-hours recalls)
- Omnivores
Exclusion
- Acute chronic disease, inflammatory or functional gastrointestinal diseases and any other disease or disorder that could affect the outcome of the study
- Use of a medication that may interfere the study outcome
- Eating disorder
- High protein intake (more than 15% of energy or maximum 1,2 g of protein per kg of body weight per day; evaluated by 3 food diaries or 24-hours recalls)
- Use of antibiotic medication during the last 3 months prior the first visit
- Use of antibiotic medication very early in life (e.g., asthmatic children or ear inflammation)
- Use of laxative or anti-diarrhoea medication within the past 3 months before the study
- Regular consumption of probiotic or prebiotic product for the past 6 weeks before the study
- Special diet that is considered to affect the study participation and/or study results, for example, high protein diets
- More than 5 h of moderate-vigorous exercise per week
- Pregnancy or breastfeeding
- Intolerance to dietary supplements that will be used in the study
- Smoking
- Abuse of alcohol or drugs (according to AUDIT score)
Key Trial Info
Start Date :
October 27 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2022
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT05367804
Start Date
October 27 2021
End Date
June 1 2022
Last Update
April 28 2023
Active Locations (1)
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1
Campus USÖ, Örebro University
Örebro, Sweden, 70362