Status:
COMPLETED
Food Intake and Epigenetic Alteration in the Spermatozoa of Singletons and Twins
Lead Sponsor:
University of Copenhagen
Collaborating Sponsors:
Deakin University
Monash Health
Conditions:
Fertility Issues
Nutrition, Healthy
Eligibility:
MALE
20-35 years
Phase:
NA
Brief Summary
The purpose of this study is to elucidate the role of acute dietary intake in male populations, and its impact on spermatozoa quality, integrity, content and epigenetic programming.
Detailed Description
The FEASST study has been designed to determine the impact of diet on the content, quality, and genetic programming of sperm. They are specifically interested in determining if a man's diet plays a ro...
Eligibility Criteria
Inclusion
- Male
- 20 to 35 years old
- BMI 18.5 to 30
- Located within the Copenhagen region
- Fluent in English and/or Danish language
- Sperm concentration of \>15 mil/mL according to the WHO's criteria for semen quality
- Semen volume of \>1.5mL mL according to the WHO's criteria for semen quality
- Clinician approval for participation in study
- Obtained informed consent
Exclusion
- Self-reported history of serious or chronic illness
- Self-reported history of Obesity
- History of any food restrictions
- History of allergies to any food products
- History of disordered eating
- Record of current use of drugs, alcohol (\>14 units per week and/or chronic binge drinking), and/or tobacco/nicotine products within the past month
- Current use of prescription medication
- Engage in \> 200 minutes of vigorous aerobic exercise per week
- Currently actively trying to conceive a child
- Diagnosis of infertility or disease of the reproductive system
- Evidence of dysregulated metabolism, characterized by the occurrence of any one of the following:
- Waist circumference \>102 cm
- Blood pressure \> 130/85 mm Hg
Key Trial Info
Start Date :
October 20 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2022
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT05368194
Start Date
October 20 2021
End Date
July 1 2022
Last Update
December 13 2023
Active Locations (1)
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1
University of Copenhagen
Copenhagen, Denmark, 2200