Status:
NOT_YET_RECRUITING
Screening Of CoRonary ArTEry diSease
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Cardiology
Coronary Artery Disease
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
This study is a randomized trial with the objective of comparing the cost-effectiveness of the 2 recommended strategies: CCTA vs functional tests, allowing the evaluation of the quality of life of the...
Detailed Description
In Europe, cardiovascular disease remains the leading cause of death with 4 million deaths per year, of which 1.8 million are due to coronary heart disease (CHD). CAD also has a cost with 46 billion /...
Eligibility Criteria
Inclusion
- Patients aged 18 to 75 years
- Symptomatic patient in whom CAD cannot be excluded by clinical evaluation alone : patient with a pre-test or "intermediate" clinical probability indicating imaging test according to European recommendations
- Patient affiliated to the social security system or beneficiary of such a system
- Written informed consent
Exclusion
- Pre-test probability "low" \< 5% or 5-15% without additive pejorative factors
- Clinical probability of "high" CAD, defined by symptoms typical of low exercise levels not responding to medical therapies
- Known history of CAD
- Severe impairment of left ventricular ejection fraction \< 40%.
- Known chronic renal failure not on dialysis (GFR \<30 ml / min /1.73 m²)
- Patient considered unfit for the study according to the investigator's judgement and in particular the impossibility of performing an anatomical and/or functional test of ischemia of the coronary disease
- Patient in a period of exclusion for another study
- Persons referred to in articles L1121-5 to L1121-8 of the public health code
- Patient participating in another interventional research
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
800 Patients enrolled
Trial Details
Trial ID
NCT05369728
Start Date
May 1 2022
End Date
October 1 2026
Last Update
May 11 2022
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