Status:
RECRUITING
Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy
Lead Sponsor:
George Washington University
Conditions:
Mediastinal Lymphadenopathy
Sarcoidosis, Pulmonary
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarco...
Detailed Description
This is prospective, single center randomized comparative study to determine the diagnostic yield and specimen quality of endobronchial ultrasound guided intranodal forceps biopsy of patients with sus...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Radiologic evidence of mediastinal and/or hilar lymphadenopathy
- Attending radiologist or pulmonologist reports a possible diagnosis of sarcoidosis
- Age 18 years or older
- Exclusion Criteria\*:
- These are the characteristics that a participant must NOT have in order to be eligible to participate in the study.
- Order Number Criteria
- Severe pulmonary hypertension
- Inability to undergo general anesthesia
- Severe coagulopathy or bleeding diathesis
- Previously diagnosed sarcoidosis
- Patient presently taking clopidogrel
- Patient deemed to be high risk for general anesthesia per anesthesiologist
- Hemodynamic instability
- Mediastinitis
- Acute Hypercarbic Respiratory Failure (pCO2 \>55mmHg)
Exclusion
Key Trial Info
Start Date :
June 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT05374447
Start Date
June 10 2022
End Date
March 1 2026
Last Update
September 9 2025
Active Locations (1)
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1
The George Washington University Hospital
Washington D.C., District of Columbia, United States, 20037