Status:
UNKNOWN
Angina, Physiology, Biology (ANgina, FIsiologia BIOlogia)
Lead Sponsor:
Hospital Arnau de Vilanova
Conditions:
Angina Pectoris
Eligibility:
All Genders
18+ years
Brief Summary
Relationship between invasive physiological assessment with FFR and IMR and biological markers as micro-RNA's according to coronary vascular compartiment affected (Group 1: Macrovasculature + / Microv...
Detailed Description
Patients with chest pain suggestive of angina after ruling out other cardiac and non-cardiac causes, referred for invasive coronary angiography, will be evaluated by coronary angiography and invasive ...
Eligibility Criteria
Inclusion
- Age ≥ 18 years.
- Patients with chest pain suggestive of angina evaluated by a cardiologist referred for diagnostic coronary angiography and possible coronary intervention.
- Echocardiogram ruling out noncoronary cardiac causes of chest pain.
- Informed consent.
Exclusion
- Contrast allergy not susceptible to premedication.
- Severe bronchial asthma or adenosine intolerance.
- Atrio-ventricular block (≥ 2nd degree) or acetylcholine intolerance.
- Acute myocardial infarction with ST-segment elevation.
- Acute myocardial infarction without ST-segment elevation.
- Cardiogenic shock.
- Total occlusion of any coronary artery that precludes measurements with pressure-temperature guidewires.
- Previous coronary artery bypass grafting.
- Women with the possibility of being pregnant.
- Renal dysfunction with an estimated glomerular filtration rate \<30 mL/min/1.73m2.
- Inability to understand the nature of the study and / or sign informed consent.
- Any other medical condition that, in the opinion of the researcher, may lead to safety issues for patients or may alter the results of the study.
Key Trial Info
Start Date :
May 8 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05374694
Start Date
May 8 2022
End Date
December 31 2023
Last Update
October 19 2022
Active Locations (1)
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1
Hospital Arnau de Vilanova
Lleida, Catalonia, Spain, 25198