Status:

UNKNOWN

An fNIRS Study of Motor Cortical Activation in Stoke Patients

Lead Sponsor:

Xuanwu Hospital, Beijing

Conditions:

Acute Ischemic Stroke

Eligibility:

All Genders

18-75 years

Brief Summary

The investigators evaluate the activation and connectivity of patients' motor regions in the acute phase of ischemic stroke by fNIRS.

Detailed Description

This study aims to analyze the progress of brain recovery from upper-limb deficit due to acute ischemic stroke, using Functional Near-infrared Spectroscopy(fNIRS) as the main neural imaging method. Fi...

Eligibility Criteria

Inclusion

  • The diagnosis of ischemic stroke should meet the diagnostic criteria of the "China Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018".
  • 18 years old≤ age ≤ 75 years old.
  • Cerebral ischemic stroke onset within 7 days.
  • First onset.
  • Upper limb motor dysfunction.

Exclusion

  • Unstable vital signs.
  • Complicated with other diseases in the nervous system.
  • Combined with other serious disease states: circulatory system, respiratory system,
  • motor system diseases, such as atrial fibrillation, heart failure, lung infection, severe liver and kidney dysfunction, lower limb venous thrombosis, etc.
  • Upper limb dysfunction caused by other reasons, such as fractures, upper limb deformities, etc.
  • Contraindicated to imaging tests, such as metal implantation, claustrophobia, and severe obesity.
  • Those who cannot complete the examination due to other reasons, such as mental disorders, cognitive dysfunction, etc.
  • Other causes: alcoholism; pregnancy; skull defects; soft tissue injuries at the site of examination; visual impairment, etc.

Key Trial Info

Start Date :

February 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2024

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT05376098

Start Date

February 1 2022

End Date

July 31 2024

Last Update

May 17 2022

Active Locations (1)

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Xuanwu Hospital, Capital Medical University

Beijing, China