Status:
RECRUITING
3D Assessment of RV Function in Patients Undergoing LVAD Implantation
Lead Sponsor:
University of Alberta
Conditions:
Heart Failure
Eligibility:
All Genders
16+ years
Brief Summary
This goal of this study is to analyze images of the right ventricle taken via 3D transesophageal echocardiography (TEE) during left ventricular assist device (LVAD) implantation.
Detailed Description
There are two chambers in the heart known as ventricles which are responsible for pumping blood to both the lungs and the rest of the body. The right ventricle pumps blood to the lungs for oxygenation...
Eligibility Criteria
Inclusion
- Patients will be eligible to be included in the study if they receive either a left-sided:
- HeartMate III (Thoratec, Pleasanton, CA)
- HeartWare HVAD (HeartWare, Oakville CA)
- Levitronix CentriMag (Levitronix LLC, Waltham, MA) LVAD.
Exclusion
- Patients will be excluded if::
- hemodynamic data needed to calculate PAPi or comprehensive echocardiographic images are missing
- additional procedures affecting cardiac geometry and/or hemodynamic measurements, such as tricuspid, mitral, and/or aortic valve repair/replacement, were performed at the time of LVAD implantation
- sternal closure at the end of the procedure is not possible
- RV mechanical support was introduced concurrently with LVAD implantation
- inadequate image quality required to obtain a 3D protocol
- known contraindication to TEE
- unexpected inability to advance probe into the mid-esophagus
Key Trial Info
Start Date :
March 22 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 19 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT05376254
Start Date
March 22 2022
End Date
January 19 2027
Last Update
May 25 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Mazankowski Alberta Heart Institute
Edmonton, Alberta, Canada, T6G 2B7