Status:

COMPLETED

Pilot Study on Proteomics of Erythrocyte Proteins in Patients With COPD Based on TMT Technology

Lead Sponsor:

Zhujiang Hospital

Conditions:

Protein; Disease

Eligibility:

All Genders

40-80 years

Brief Summary

Chronic obstructive pulmonary disease (COPD), a common and complex disease characterized by persistent airflow limitation, is a leading cause of mortality worldwide. COPD and its comorbidity are assoc...

Eligibility Criteria

Inclusion

  • case group
  • Age from 40 to 80 years old; gender is not limited.
  • Stable COPD
  • Sign the informed consent with the willingness of obeying the protocol. -

Exclusion

  • Subjects with known other chronic respiratory diseases except for COPD (such as asthma, tuberculosis, bronchiectasis, interstitial lung disease, occupational lung diseases, sarcoidosis, lung cancer, et al);
  • Subjects had been accepted lung lobectomy or transplantation;
  • Subjects be ill with severe, or uncontrolled systemic diseases other than COPD (such as psychiatry diseases, chronic liver diseases, heart failure, auto-immunity diseases, chronic renal diseases, et al );
  • Alcoholism, drug or solvents addition;
  • Acute exacerbation COPD patients (AECOPD) -
  • control group Inclusion criteria
  • Age from 40 to 80 years old; gender is not limited.
  • Sign the informed consent with the willingness of obeying the protocol. - Exclusion criteria
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  • Subjects with known other chronic respiratory diseases (such as COPD, asthma, tuberculosis, bronchiectasis, interstitial lung disease, occupational lung diseases, sarcoidosis, lung cancer, et al);
  • Subjects had been accepted lung lobectomy or transplantation;
  • Subjects be ill with severe, or uncontrolled systemic diseases other than COPD (such as psychiatry diseases, chronic liver diseases, heart failure, auto-immunity diseases, chronic renal diseases, et al );
  • Alcoholism, drug or solvents addition;

Key Trial Info

Start Date :

July 15 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 15 2022

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05376618

Start Date

July 15 2021

End Date

July 15 2022

Last Update

March 15 2024

Active Locations (1)

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Zhujiang Hospital,Southern Medical Universtiy

Guangzhou, Guangdong, China, 510282

Pilot Study on Proteomics of Erythrocyte Proteins in Patients With COPD Based on TMT Technology | DecenTrialz