Status:
RECRUITING
Efficacy of Surgical Joint Denervation in Painful Digital Osteoarthritis
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Osteoarthritis Hand
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Digital osteoarthritis is the second localization of symptomatic osteoarthritis, after the knee. Its cardinal symptoms are particularly intense pain and functional impairment in the case of the erosiv...
Detailed Description
Osteoarthritis is the most common joint pathology of the musculoskeletal system. It affects 6 million French people and constitutes a public health problem. Osteoarthritis of the hands or digitalis is...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Patients with symptomatic digital osteoarthritis according to the criteria of the American College of Rheumatology
- 1 painful PIP joint (Analog digital scale ≥ 4/10) for more than 3 months
- having failed the usual medical treatment for a minimum of 3 months (level 1 analgesics, NSAIDs, infiltrations)
- Signature of informed consent
- patient affiliated to a social security scheme
- knowing how to read French (for the questionnaires)
Exclusion
- digital osteoarthritis secondary to other known causes (eg gout, reactive arthritis, RA, psoriatic arthritis, spondyloarthropathies, septic arthritis)
- anesthetic contraindications to surgery or to performing an MRI
- Existence of a pain syndrome in the upper limbs, which would interfere with the assessment of AD.
- Fibromyalgia
- Use of oral, intramuscular or intra-articular or intravenous corticosteroids, immunosuppressants (methotrexate, sulfasalazine, leflunomide, biomedicines), hyaluronic acid infiltration in the finger joints in the previous month
- Introduction of a new treatment for osteoarthritis of the hand in the previous month, including physiotherapy and fitting of a new finger orthosis.
- History of denervation of the proximal interphalangeal joint (PIP)
- Patient under legal protection (guardianship or curatorship) and patient deprived of liberty
- Patient under AME
- Participation in another interventional research involving the human person or period of exclusion at the end of a previous research involving the human person.
Key Trial Info
Start Date :
June 5 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 15 2026
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT05378841
Start Date
June 5 2023
End Date
June 15 2026
Last Update
July 14 2025
Active Locations (1)
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1
Rheumatology department Saint-Antoine Hospital
Paris, France, 75012