Status:

COMPLETED

Effective Dose of Remimazolam for Sedation in Patients Undergoing Lower Extremity Surgery Under Spinal Anesthesia

Lead Sponsor:

Asan Medical Center

Conditions:

Remimazolam

Orthopedic Procedures

Eligibility:

All Genders

19-79 years

Phase:

PHASE4

Brief Summary

Currently used drugs for monitored general anesthesia include propofol, midazolam, and dexmedetomidine. Each drug has different advantages and disadvantages. Remimazolam causes a relatively small decre...

Eligibility Criteria

Inclusion

  • ASA PS 1-3
  • Patients undergoing lower extremity surgery under spinal anesthesia and sedation using remimazolam

Exclusion

  • Patients who refuse to participate in this study
  • Patients with hypersensitivity to benzodiazepine or flumazenil
  • Patients with severe renal/hepatic disease
  • Patients with drug/alcohol abuse
  • Patients who take antidepressants, anticonvulsants, psychoactive drugs chronically
  • Patients with difficulty in communication
  • Patients with severe obstructive sleep apnea or other airway problems
  • Patients contraindicated to regional anesthesia
  • Patients judged to be inappropriate for this study

Key Trial Info

Start Date :

May 11 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 24 2022

Estimated Enrollment :

51 Patients enrolled

Trial Details

Trial ID

NCT05379777

Start Date

May 11 2022

End Date

August 24 2022

Last Update

December 19 2022

Active Locations (1)

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1

Asan Medical Center

Seoul, South Korea, 05505