Status:
RECRUITING
CHART Study of Coronary CT Angiography in Coronary Artery Disease
Lead Sponsor:
Shanghai Zhongshan Hospital
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18+ years
Brief Summary
In a cohort of patients referred to coronary computed tomography angiography (CCTA), the investigators aim: 1. To describe the natural history of the coronary atherosclerotic plaque development and p...
Detailed Description
Invasive physiologic indices such as fractional flow reserve (FFR) are used to define ischemia-causing stenosis and guide percutaneous coronary intervention (PCI) in the clinical practice. FFR-guided ...
Eligibility Criteria
Inclusion
- Patients with an indication for CCTA.
- Qualified patients who have signed a written informed consent form.
Exclusion
- Left ventricular ejection fraction \< 35%
- Acute ST-elevation myocardial infarction within 72 hours or previous coronary artery bypass graft surgery
- Abnormal epicardial coronary flow (TIMI flow \< 3)
- Planned coronary artery bypass graft surgery after diagnostic angiography
- Poor quality of CCTA or other reasons by core lab that are unsuitable for plaque, physiological or fat analysis
- Patients with a stent in the target vessel
Key Trial Info
Start Date :
January 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2030
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT05380622
Start Date
January 1 2015
End Date
December 31 2030
Last Update
May 25 2022
Active Locations (1)
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1
Shanghai Zhongshan Hospital
Shanghai, China