Status:

RECRUITING

Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After ARS in Patients With GERD

Lead Sponsor:

Shandong University

Conditions:

Esophageal Motility Disorders

Eligibility:

All Genders

18+ years

Brief Summary

rapid swallow (MRS) can assess the contractile reserve capacity of the oesophageal body and identify and diagnose oesophageal motility disorders, but the impact of preoperative oesophageal reserve cap...

Detailed Description

Lower oesophageal sphincter relaxation is an important cause of GERD and ineffective oesophageal motility may be associated with GERD, but the mechanism of oesophageal corporal motility disorders is u...

Eligibility Criteria

Inclusion

  • Age over 18 years old
  • Patients to be treated surgically for gastroesophageal reflux disease
  • Ineffective esophageal motility diagnosed by high resolution esophageal manometry according to Chicago Classification version 4.0
  • Obtaining Informed Consent

Exclusion

  • Previous other upper gastrointestinal surgery
  • Pregnant women and other people with contraindications to surgery and tests
  • Other specifically defined esophageal motility disorders, such as nutcracker esophagus

Key Trial Info

Start Date :

April 22 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2026

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT05380791

Start Date

April 22 2022

End Date

June 1 2026

Last Update

May 19 2022

Active Locations (1)

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Department of Gastroenterology, Qilu Hospital, Shandong University

Jinan, Shandong, China, 250012