Status:
RECRUITING
Menstrual-phase-dependent Differences in Response to Sleep Loss
Lead Sponsor:
Brigham and Women's Hospital
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Sleep Deprivation
Eligibility:
FEMALE
18-35 years
Phase:
NA
Brief Summary
This study is designed to assess how healthy premenopausal women respond to different patterns of sleep loss at different times in the menstrual cycle.
Detailed Description
During a 1.5-week inpatient laboratory protocol, participants will undergo one of two parallel sleep conditions during either the follicular or luteal phase of the menstrual cycle (4 study arms total)...
Eligibility Criteria
Inclusion
- Female
- 18-35 years old
- Regular menstrual cycle between 26-35 days in duration
- Not using any form of hormonal contraception for at least the prior 3 months
- Regular sleep patterns (7-9 hours/night)
- Not taking any medications or supplements
- Weight \>110 lb
- BMI between 18.5 and 29.5 kg/m2
Exclusion
- Primary sleep disorder
- History of shift work
- Transmeridian travel in the previous 3 months
- Presence of acute or chronic disease, including but not limited to: diabetes, metabolic disorders, psychiatric illness, reproductive disorders
- Current pregnancy, \< 6 months postpartum, and/or breastfeeding
- Blood donation in the past 8 weeks
- Extreme morning or evening chronotype
Key Trial Info
Start Date :
October 17 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 31 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05381532
Start Date
October 17 2022
End Date
March 31 2026
Last Update
September 19 2025
Active Locations (1)
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1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115