Status:
COMPLETED
Timing of Renal Replacement Therapy In Mechanically Ventilated Patients
Lead Sponsor:
Alexandria University
Conditions:
Timing of RRT in Mechanically Ventilated Patients
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a randomized controlled study that will be conducted on acute kidney injury (AKI) patients, who are mechanically ventilated, to assess the impact of implementation of early renal replacement t...
Detailed Description
The study subjects will be randomly divided into two groups (arms). The first one will be patients who will receive early renal replacement therapy (RRT) according to predefined criteria that will be...
Eligibility Criteria
Inclusion
- All patients must be on invasive mechanical ventilation.
- Patients in AKI stage 2 , according to KDIGO classification.
- Recruited subjects will include either those who present with AKI on their ICU admission or those who develop AKI during their ICU stay
Exclusion
- Those who are known to be in grade 5 CKD according to KDIGO classification. All other grades of CKD from 1 to 4 will be included only if they develop or present with stage 2 AKI on top of their CKD grade
- Those who develop AKI due to obstructive or traumatic causes.
- Patients with septic shock who are on high doses of vasopressors or inotropes (norepinephrine infusion more than 1 mcg/kg/minute, dopamine or dobutamine infusion more than 5 mcg/kg/minute).
- Pregnant females
Key Trial Info
Start Date :
June 28 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 28 2023
Estimated Enrollment :
94 Patients enrolled
Trial Details
Trial ID
NCT05382598
Start Date
June 28 2022
End Date
November 28 2023
Last Update
December 4 2023
Active Locations (1)
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1
Alexandria Faculty of Medicine
Alexandria, Alexandria Governorate, Egypt, 21131