Status:
UNKNOWN
Facilitating Adjustment to Simulated Jet Lag
Lead Sponsor:
University of Arizona
Collaborating Sponsors:
University of California, San Diego
Conditions:
Circadian Rhythm Sleep Disorder, Jet Lag Type
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The aims of this study are to compare 3 different treatments for circadian adjustment to a laboratory protocol which will mimic westward air travel across 8 time zones. One treatment will involve simp...
Detailed Description
Design Overview. Following a 1 week home baseline, N=36 young adults will spend 6 days in the laboratory (Figure 3 and Table 1). Following am 8 h baseline polysomnographic recording (PSG) on Night 1, ...
Eligibility Criteria
Inclusion
- age 18-45 years
- At least moderate level of habitual physical activity (twice per week, 20 min of aerobic exercise at 60% of maximal effort or higher
Exclusion
- (1)Having more than one risk factor for coronary artery disease: (2) having any symptom or sign of cardiopulmonary disease; (3) recent shift-work experience (previous 2 months) or travel across multiple time zones (previous 4 weeks); (4) having an abnormal sleep-wake schedule (i.e., reported bedtime before 9:00 pm or after 2:00 am; wake time before 5:00 am or after 10:00 am); (5) being an extreme night owl or morning lark, as assessed by the Horne-Ostberg Mornngness-Eveningness Scale;70 (6) having a high risk sleep apnea or another sleep disorder; (7) depressed mood \[Center for Epidemiologic Studies-Depression Scale (CES-D) \> 16\];71 (7) use of medications likely to distort melatonin excretion or cardiovascular responses to exercise; (8) use of sleeping pills more than 1 night per week; (9) having high sensitivity to light; (10) abuse of alcohol or drugs (amount per week; related problems such as missing work); (11) any physical or mental health condition that would contraindicate participation in exercise or other rigors of the experiment.
Key Trial Info
Start Date :
July 10 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2023
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT05382923
Start Date
July 10 2021
End Date
May 1 2023
Last Update
May 19 2022
Active Locations (1)
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1
Center Sleep and Circadian Sciences
Tucson, Arizona, United States, 85724