Status:

UNKNOWN

FLT3-ITD Gene Mutation and CD135 Expression in Acute Myeloid Leukemia.

Lead Sponsor:

Assiut University

Conditions:

Acute Myeloid Leukemia

Eligibility:

All Genders

Brief Summary

1. To evaluate expression levels of CD135 2. To assess the frequency of FLT3 gene mutations (ITD) 3. association between FLT3-ITD mutation and CD135 expression and their correlation with hematological...

Detailed Description

Acute leukemias are clonal malignant diseases of immature hematopoietic system ,characterized by clonal evolution and considerable genetic, epigenetic, and phenotypic heterogeneity,and constitute a co...

Eligibility Criteria

Inclusion

  • Newly diagnosed Patients with acute myeloid leukemia (AML), who fullfill the WHO criteria.

Exclusion

  • AML on top of myeloproliferative neoplasms or MDS.
  • previously diagnosed AML on treatment
  • Patients with any other type of malignant tumors

Key Trial Info

Start Date :

June 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2024

Estimated Enrollment :

82 Patients enrolled

Trial Details

Trial ID

NCT05383014

Start Date

June 1 2022

End Date

July 1 2024

Last Update

May 19 2022

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