Status:
RECRUITING
Evaluation of RRFT for Co-occurring SUD and PTSD Among Teens
Lead Sponsor:
Medical University of South Carolina
Collaborating Sponsors:
University of Colorado, Denver
Indiana University School of Medicine
Conditions:
Substance Use Disorders
PTSD
Eligibility:
All Genders
13-75 years
Phase:
NA
Brief Summary
Psychosocial traumatic events during childhood, serve as strong and consistent predictors of substance use problems (SUP) during adolescence and adulthood.PTSD that extends from such trauma often co-o...
Eligibility Criteria
Inclusion
- Aged 13-19 years (adolescents);
- Experienced lifetime DSM-V PTSD Criteria A-defined potentially traumatic event, such as interpersonal violence, with memory of incident(s), such as child sexual abuse (forced or unwanted vaginal or anal penetration by an object, finger, or penis; oral sex; touching of the respondent's breasts or genitalia; or respondents' touching of another person's genitalia); child physical abuse (nonaccidental physical injury to the child or any action that results in a physical impairment of the child), witnessed domestic violence (exposure to conduct by a household member against another household member that involves attempted or completed assault or murder); witnessed community violence; dating violence; as well as disasters, accidents, etc.;
- Five or more current DSM-V PTSD symptoms as assessed on the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS)/UCLA PTSD Index;
- Substance use, defined as alcohol or non-tobacco drug use, in the past 28 days prior to study screening per self-report. If in a restrictive setting for the 28 days prior to study screening, substance use will be anchored to use prior to entering restrictive setting;
- A current (past year) non-nicotine substance use disorder (SUD) as assessed on the K-SADS;
- English-speaking.
Exclusion
- Presence of Pervasive Developmental Disability or Moderate/Severe Mental Retardation or other cognitive limitation that would preclude meaningful engagement in RRFT or cognitive-behavioral therapy
- Actively suicidal/homicidal;
- Active psychosis.
Key Trial Info
Start Date :
October 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
212 Patients enrolled
Trial Details
Trial ID
NCT05384223
Start Date
October 15 2022
End Date
June 30 2026
Last Update
June 29 2025
Active Locations (2)
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1
CU Medicine Psychiatry - Outpatient Clinic
Aurora, Colorado, United States, 80045
2
ARTS - Synergy Outpatient Services
Denver, Colorado, United States, 80236