Status:
RECRUITING
HPV Screening With Triage by HPV Genotyping Versus Visual Inspection With Acetic Acid
Lead Sponsor:
Prof. Patrick Petignat
Collaborating Sponsors:
University Hospital, Geneva
Bafoussam Regional Hospital, Cameroon
Conditions:
Cervical Cancer
Eligibility:
FEMALE
25-49 years
Phase:
NA
Brief Summary
Cervical cancer is the leading cause of cancer death among women in sub-Saharan Africa, despite the existence of effective prevention and screening methods. Because vaccination rates against human pap...
Detailed Description
HPV used as a stand-alone test has a limited specificity and positive predictive value and as a consequence, a significant number of HPV-positive women have no cervical precancerous lesions or cancer ...
Eligibility Criteria
Inclusion
- HIV-negative women aged 30-49 and HIV-positive women aged 25-49 years old
- Ability to understand study procedures and accepting voluntarily to participate by signing an informed consent form (ICF).
Exclusion
- Pregnancy at the time of screening
- Previous hysterectomy
- Known cervical cancer
- Symptoms of cervical cancer (e.g. metrorrhagia, known pelvic mass)
- Conditions that can interfere with visualization of the cervix
- Severe pre-existing medical conditions (e.g. advanced cancer, terminal renal failure)
- Women who are not able to comply with the study protocol.
Key Trial Info
Start Date :
December 6 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
5500 Patients enrolled
Trial Details
Trial ID
NCT05385406
Start Date
December 6 2022
End Date
June 30 2026
Last Update
May 9 2024
Active Locations (2)
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1
Dschang Annex Regional Hospital
Dschang, Menoua, Cameroon
2
Bafoussam Regional Hospital
Bafoussam, Mifi, Cameroon