Status:
RECRUITING
Adaptive Optics Retinal Imaging in Inherited and Acquired Retinal Disorders
Lead Sponsor:
The Hospital for Sick Children
Conditions:
Genetic Disease
Inherited Disease
Eligibility:
All Genders
5-70 years
Brief Summary
This is a Prospective Observational study. The aim of the study is to understand the underlying photoreceptor, retinal pigment epithelium or retinal vascular aberrations in inherited and acquired reti...
Detailed Description
The investigators plan to recruit approximately 200 participants (approximately 175 study subjects and 25 Control group) having an inherited or acquired retinal disease. The study participants will be...
Eligibility Criteria
Inclusion
- Consent provided
- Aged 5 - 70 years
- Diagnosed with well documented retinal disorder
- Control group
- Subjects aged 5 years - 70 years with normal eye examination.
- Patients with strabismus and otherwise normal visual acuity and eye examination
- Patients with unilateral eye diseases such as cataract, with a normal eye exam in the fellow eye.
Exclusion
- Inability of the subject to maintain a stable position while seated
- Uncontrolled nystagmus, trembling or movements of the eyes or the head
- Presence of cataract or any opacity in the front of the eye that obscures retinal imaging
- Any general disease such neurological disease which could affect vision and the retina.
- History of previous uveitis, glaucoma, previous intra-ocular surgery or photodynamic therapy
- High refractive errors (\> +15D or \< -15D) that cannot be corrected by the adaptive optics system.
- Patients who have a history of photosensitivity or take any medicine that cause photosensitivity as a side effect
- Patients who are aphakic after cataract surgery
Key Trial Info
Start Date :
June 13 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 13 2033
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT05386134
Start Date
June 13 2022
End Date
June 13 2033
Last Update
January 10 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8